hi zusammen,
ich freu mich riesig, dass ihr an diesem thema interesiert seid
und kopier euch mal etwas hier rein von den RO - news:
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Smoking is a strong risk factor for rheumatoid nodules in early rheumatoid arthritis.
Nyhall-Wahlin BM, Jacobsson LT, Petersson IF, Turesson C.
Department of Rheumatology, Falun Hospital, Sweden.
OBJECTIVES: To examine whether smoking is a risk factor for rheumatoid nodules(RN) in early rheumatoid arthritis(RA), and if so to determine the quantitative effect of smoking. METHODS: From a cohort (n=1589) in a structured programme for follow-up of newly diagnosed RA (symptoms of swollen joints </=12 months) 112 individuals with RN at inclusion were
identified. Nodular patients were each compared to two age- and sex-matched controls without nodules from the same cohort.
A detailed self- administered tobacco use questionnaire was answered by 210 patients (63%). RESULTS: Seventy patients were current smokers, 71 former smokers and 69 had never smoked.
Current smoking and former smoking were more common in patients with RN compared to controls (86% v. 59%) in both sexes.
Positive rheumatoid factor (RF) was found more often among RN cases than controls (78% v. 64%). Using detailed information from the questionnaires with conditional logistic regression analyses, ever having smoked was associated with a significantly increased risk of the presence of RN (OR 7.3, 95% CI 2.3 - 23.6; p=0.001). The risk of having nodules was not obviously dose-dependent, when smoking duration as well as smoking amount were examined.
A stratified analysis showed that only RF-positive smokers had an increased risk of RN. Smoking was associated with RN among both men (p=0.006) and women (p=0.001). Tobacco use other than smoking (n=31) was not associated with an increased risk of nodules (OR 0.8, 95% CI 0.2-3.4; p=0.813).
CONCLUSIONS: There is a strong association between smoking and RN in early seropositive RA.
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das fazit übersetzt: es gibt einen starken zusammenhang zwischen
rauchen und rheumaknoten bei früher seropositver ra (= cp/rheumatoide
arthritis)
naja, das rauchen ungesund ist, wissen wir ja!
grüsschen marie